Kusajili – Centralise les essais cliniques mondiaux

A Trial to Compare the Effectiveness of Two Rehabilitation Programs for Multiple Sclerosis Patients The purpose of this study was to compare the effectiveness of two rehabilitation programs (one month) in patients with multiple sclerosis. The first program is combined with physiotherapy, endurance training and resistance training. The second one is physiotherapy in private practice. Another purpose is to assess the length of the benefits of the combined program.

• Pays France,
• Organes Aucun
• Spécialités Aucun

A Study to Evaluate MEDI0562 in Combination With Immune Therapeutic Agents in Adult Subjects With Advanced Solid Tumors The purpose of this study is to evaluate MEDI0562 in combination with immune therapeutic agents in adult subjects with select advanced solid tumors.

• Pays Australia, France, Netherlands, United States,
• Organes Aucun
• Spécialités Aucun

Study of Meniscal Allografts Total or subtotal meniscectomies in young patients are currently responsible of pain and limitation of activities. There isn't any other treatment than meniscal replacement. But there is no randomized clinical trial on meniscal allograft to validate the efficiency of this treatment.

• Pays France,
• Organes Aucun
• Spécialités Aucun

Circulating Tumoral DNA in Choroidal Melanoma (ctDNA MU) Quantification and follow-up during 3 years of circulating tumoral DNA in patients with choroidal melanoma

• Pays France,
• Organes Aucun
• Spécialités Aucun

Validation of Nicom Device to Measure Stoke Volume Variation The purpose of this study is to evaluate the ability of NICOM (Noninvasive cardiac output monitor) to detect stroke volume variation induced by leg raising or fluid expansion during surgery

• Pays France,
• Organes Aucun
• Spécialités Aucun

Efficacy of Periodontal Treatment on Glycaemic Control in Diabetic Patients This study will assess the efficacy of periodontal treatment in diabetic patient. Patients will be randomized in the periodontal group or in the control group. The control group will received a periodontal treatment after the study.

• Pays France,
• Organes Aucun
• Spécialités Aucun

Safety and Efficacy of BKM120 in Relapsed and Refractory NHL This is a phase II study evaluating the safety, tolerability and efficacy of BKM120 in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma (MCL) or follicular lymphoma (FL).

• Pays Belgium, France, Germany, Italy, Korea, Republic of, Spain, Turkey, United States,
• Organes Aucun
• Spécialités Aucun

Pilot Study of Maraviroc/Raltegravir for Naive HIV-1 Patients Background and Rationale Raltegravir and Maraviroc, the first in class of 2 new families of antiretroviral drugs have demonstrated a high potency in treatment experienced and naive patients. Both drugs appeared well tolerated with low metabolic toxicity. No data are currently available concerning the combination of these 2 drugs. Hypothesis Maraviroc + Raltegravir should be potent enough to maintain virological efficacy in naive patients infected by CCR5 HIV-1 previously treated for 6 months with a Maraviroc-Raltegravir-Tenofovir-Emtricitabine combination.

• Pays France,
• Organes Aucun
• Spécialités Aucun

Repetitive Transcranial Magnetic Stimulation in Obsessive Compulsive Disorder Evaluate the therapeutic effect of a functional Magnetic Resonance Imaging (fMRI)-guided and robotized neuronavigated theta burst Transcranial Magnetic Stimulation (TMS) targeting right inferior frontal region in resistant obsessive compulsive disorder (OCD) in a double-blind, randomized, placebo-controlled, monocentric study.

• Pays France,
• Organes Aucun
• Spécialités Aucun

Assessment of the Psychological, Cognitive and Social Resources of Applicants for Huntington's Disease and Presymptomatic Genetic Testing The purpose of this study is to assess the psychological, cognitive and social resources of applicants for Huntington's Disease and Presymptomatic Testing.

• Pays France,
• Organes Aucun
• Spécialités Aucun